Be a PeRL Crusher — your name, your impact, honored on the wall

$5,000 = 1 Brick. 1 Tumor Sequenced. 1 Step Closer to Cures.

Every day, families face the devastating reality of childhood brain cancer. Medulloblastoma is the most common malignant brain tumor in kids — and for many, treatment options are limited. The most aggressive forms often resist therapy. We need answers now.

At Texas Children's Cancer and Hematology Center, Dr. Michael Taylor and his lab are leading a bold initiative: mapping medulloblastoma at single-cell resolution to uncover how these tumors start — and how to stop them before they take hold.

Researchers have discovered that these cancers may begin as tiny, abnormal patches in the developing brain called Persistent Rhombic Lips (PeRLs). Understanding PeRLs could unlock lifesaving biomarkers and new treatments.

Our goal: sequence 1,000 tumors to build the most detailed map of medulloblastoma ever created. Each tumor we sequence adds a "brick" to this map. Each tumor costs $5,000 to sequence. Every gift moves us forward.

Join us. Help crush PeRLs and stop brain cancer before it starts.